Expression of Mitochondrial Branched-Chain Aminotransferase and α-Keto-Acid Dehydrogenase in Rat Brain: Implications for Neurotransmitter Metabolism

• Ngā kaituhi matua: Jeffrey Thomas Cole (Author), Andrew J Sweatt (Author), Susan M Hutson (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2012-05-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

In the brain, metabolism of the essential branched chain amino acids (BCAAs) leucine, isoleucine and valine, is regulated in part by protein synthesis requirements. Excess BCAAs are catabolized or excreted. The first step in BCAA catabolism is catalyzed by the branched chain aminotransferase (BCAT)...