Preclinical development of BCG.HIVA2auxo.int, harboring an integrative expression vector, for a HIV-TB Pediatric vaccine. Enhancement of stability and specific HIV-1 T-cell immunity
One of the critical issues that should be addressed in the development of a BCG-based HIV vaccine is genetic plasmid stability. Therefore, to address this issue we have considered using integrative vectors and the auxotrophic mutant of BCG complemented with a plasmid carrying a wild-type complementi...
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Main Authors: | Aakash Mahant (Author), Narcís Saubi (Author), Yoshiki Eto (Author), Núria Guitart (Author), Josep Ma Gatell (Author), Tomáš Hanke (Author), Joan Joseph (Author) |
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Format: | Book |
Published: |
Taylor & Francis Group,
2017-08-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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