Detection of a heterozygous germline APC mutation in a three-generation family with familial adenomatous polyposis using targeted massive parallel sequencing in Vietnam

• Päätekijät: Hoa Giang (Tekijä), Vu T Nguyen (Tekijä), Sinh D Nguyen (Tekijä), Huu-Phuc Nguyen (Tekijä), Binh T Vo (Tekijä), Truc M Nguyen (Tekijä), Nguyen H Nguyen (Tekijä), Kiet D Truong (Tekijä), Thanh-Thuy T Do (Tekijä), Minh-Duy Phan (Tekijä), Hoai-Nghia Nguyen (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2018-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background Familial adenomatous polyposis (FAP) is an autosomal dominant hereditary syndrome characterised by the development of hundreds to thousands of adenomatous colonic polyps during the second decade of life. FAP is caused by germ line mutations in the adenomatous polyposis coli (APC)...