METTL3 Induces AAA Development and Progression by Modulating N6-Methyladenosine-Dependent Primary miR34a Processing

• Main Authors: Lintao Zhong (Author), Xiang He (Author), Haoyu Song (Author), Yili Sun (Author), Guojun Chen (Author), Xiaoyun Si (Author), Jie Sun (Author), Xiaoqiang Chen (Author), Wangjun Liao (Author), Yulin Liao (Author), Jianping Bin (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Identifying effective drugs to delay the progression of aortic aneurysms is a formidable challenge in vascular medicine. Methyltransferase-like 3 (METTL3) plays a key role in catalyzing the formation of N6-methyladenosine (m6A), but despite the functional importance of METTL3 and m6A in various fund...