Protective Effect of Fluorofenidone Against Acute Lung Injury Through Suppressing the MAPK/NF-κB Pathway

• Main Authors: Xin Lv (Author), Tingting Yao (Author), Rongling He (Author), Yijun He (Author), Mengyu Li (Author), Yuanyuan Han (Author), Yan Zhang (Author), Lingzhi Long (Author), Guoliang Jiang (Author), Xiaoyun Cheng (Author), Yanyun Xie (Author), Ling Huang (Author), Zhangzhe Peng (Author), Gaoyun Hu (Author), Qianbin Li (Author), Lijian Tao (Author), Jie Meng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lung injury (ALI) is a severe disease that presents serious damage and excessive inflammation in lungs with high mortality without effective pharmacological therapy. Fluorofenidone (AKFPD) is a novel pyridone agent that has anti-fibrosis, anti-inflammation, and other pharmacological activities...