Population pharmacokinetics for oral paclitaxel in patients with advanced/metastatic solid tumors

• Main Authors: Jimmy He (Author), Christopher G. C. A. Jackson (Author), Sanjeev Deva (Author), Tak Hung (Author), Katriona Clarke (Author), Eva Segelov (Author), Tsu‐Yi Chao (Author), Ming‐Shen Dai (Author), Hsien‐Tang Yeh (Author), Wen Wee Ma (Author), Douglas Kramer (Author), Wing‐Kai Chan (Author), Rudolf Kwan (Author), David Cutler (Author), Jay Zhi (Author)
• Format: Book
• Published: Wiley, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Oraxol consists of an oral dosage form of the chemotherapeutic agent paclitaxel administered with a novel P‐glycoprotein inhibitor encequidar methanesulfonate monohydrate (formerly named HM30181A), which allows oral treatment of cancers that would otherwise be treated with intravenous pacli...