Single nuclei RNA sequencing of the rat AP and NTS following GDF15 treatment

• Main Authors: Benjamin C. Reiner (Author), Richard C. Crist (Author), Tito Borner (Author), Robert P. Doyle (Author), Matthew R. Hayes (Author), Bart C. De Jonghe (Author)
• Format: Book
• Published: Elsevier, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Growth differentiation factor 15 (GDF15) is known to play a role in feeding, nausea, and body weight, with action through the GFRAL-RET receptor complex in the area postrema (AP) and nucleus tractus solitarius (NTS). To further elucidate the underlying cell type-specific molecular mechani...