Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci

• Главные авторы: Houlston Richard S (Автор), Tomlinson Ian PM (Автор), Järvinen Heikki (Автор), Mecklin Jukka-Pekka (Автор), Li Yilong (Автор), Tuupanen Sari (Автор), Niittymäki Iina (Автор), Karhu Auli (Автор), Aaltonen Lauri A (Автор)
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• Опубликовано: BMC, 2011-02-01T00:00:00Z.
• Предметы: article
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<p>Abstract</p> <p>Background</p> <p>Common single-nucleotide polymorphisms (SNPs) in ten chromosomal loci have been shown to predispose to colorectal cancer (CRC) in genome-wide association studies. A plausible biological mechanism of CRC susceptibility associated with...