The Effect of Novel Oleanolic Acid Oximes Conjugated with Indomethacin on the Nrf2-ARE And NF-κB Signaling Pathways in Normal Hepatocytes and Human Hepatocellular Cancer Cells

Nrf2 and NF-κB play a key role in inflammation-driven cancers. Conjugation of anti-inflammatory drugs with oleanolic acid oxime (OAO) may enhance their therapeutic potential as a result of downregulation of these pathways. Novel OAO derivatives conjugated with indomethacin (IND) were synthesized, an...

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Main Authors: Maria Narożna (Author), Violetta Krajka-Kuźniak (Author), Barbara Bednarczyk-Cwynar (Author), Robert Kleszcz (Author), Wanda Baer-Dubowska (Author)
Format: Book
Published: MDPI AG, 2020-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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