Paraoxonases (PON) 1, 2, and 3 Polymorphisms and PON-1 Activities in Patients with Sickle Cell Disease

• Main Authors: Cadiele Oliana Reichert (Author), Carolina Garcia de Macedo (Author), Débora Levy (Author), Bruno Carnevale Sini (Author), Andréia Moreira Monteiro (Author), Magnus Gidlund (Author), Luciana Morganti Ferreira Maselli (Author), Sandra Fátima Menosi Gualandro (Author), Sérgio Paulo Bydlowski (Author)
• Format: Book
• Published: MDPI AG, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

(1) Background: Oxidative stress, chronic inflammation, vasoocclusion, and free iron are all features present in sickle cell disease. Paraoxonases (PON) are a family (PON-1, PON-2, PON-3) of antioxidant enzymes with anti-inflammatory action. Here, for the first time, we described PON-1 activities an...