ac4C acetylation of RUNX2 catalyzed by NAT10 spurs osteogenesis of BMSCs and prevents ovariectomy-induced bone loss

• Main Authors: W. Yang (Author), H.Y. Li (Author), Y.F. Wu (Author), R.J. Mi (Author), W.Z. Liu (Author), X. Shen (Author), Y.X. Lu (Author), Y.H. Jiang (Author), M.J. Ma (Author), H.Y. Shen (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

N-acetyltransferase 10 (NAT10) is the key enzyme for N4-acetylcytidine (ac4C) modification of mRNA, which participates in various cellular processes and is related to many diseases. Here, we explore the relationships among osteoblast differentiation, NAT10, and ac4C, and we found that NAT0 expressio...