Endothelium-Independent Hypoxic Contraction Is Prevented Specifically by Nitroglycerin via Inhibition of Akt Kinase in Porcine Coronary Artery

• 主要な著者: Huixia Liu (著者), Yanjing Li (著者), Yuanming An (著者), Peixin He (著者), Liling Wu (著者), Yuansheng Gao (著者), Dou Dou (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2016-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Objective. Hypoxia-induced sustained contraction of porcine coronary artery is endothelium-independent and mediated by PI3K/Akt/Rho kinase. Nitroglycerin (NTG) is a vasodilator used to treat angina pectoris and acute heart failure. The present study was to determine the role of NTG in hypoxia-induce...