Comparison of the Analgesic Effect of Diclofenac Sodium-Eudragit® RS100 Solid Dispersion and Nanoparticles Using Formalin Test in the Rats

• Main Authors: Khosro Adibkia (Author), Alireza Mohajjel Nayebi (Author), Mohammad Barzegar-Jalali (Author), Siavash Hosseinzadeh (Author), Saeed Ghanbarzadeh (Author), Afshin Shiva (Author)
• Formato: Livro
• Publicado em: Tabriz University of Medical Sciences, 2015-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Purpose: In this study the intensity and duration of analgesic effect of diclofenac Na - Eudragit® RS100 solid dispersion and nanoparticles were evaluated by using formalin test in the rats. Methods: The animals received different formulations of diclofenac Na and subsequently 50 μl of formalin solu...