Mass Production of Rg1-Loaded Small Extracellular Vesicles Using a 3D Bioreactor System for Enhanced Cardioprotective Efficacy of Doxorubicin-Induced Cardiotoxicity

• Päätekijät: Yunfeng Di (Tekijä), Shuang Zhao (Tekijä), Huilan Fan (Tekijä), Wei Li (Tekijä), Guangjian Jiang (Tekijä), Yong Wang (Tekijä), Chun Li (Tekijä), Wei Wang (Tekijä), Jingyu Wang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2024-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background: Small extracellular vesicles (sEVs) obtained from human umbilical cord mesenchymal stromal cells (MSCs) have shown cardioprotective efficacy in doxorubicin-induced cardiotoxicity (DIC). However, their clinical application is limited due to the low yield and high consumption. This study a...