Mass Production of Rg1-Loaded Small Extracellular Vesicles Using a 3D Bioreactor System for Enhanced Cardioprotective Efficacy of Doxorubicin-Induced Cardiotoxicity

• Κύριοι συγγραφείς: Yunfeng Di (Συγγραφέας), Shuang Zhao (Συγγραφέας), Huilan Fan (Συγγραφέας), Wei Li (Συγγραφέας), Guangjian Jiang (Συγγραφέας), Yong Wang (Συγγραφέας), Chun Li (Συγγραφέας), Wei Wang (Συγγραφέας), Jingyu Wang (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2024-04-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Background: Small extracellular vesicles (sEVs) obtained from human umbilical cord mesenchymal stromal cells (MSCs) have shown cardioprotective efficacy in doxorubicin-induced cardiotoxicity (DIC). However, their clinical application is limited due to the low yield and high consumption. This study a...