Hepatoprotective Role of Carvedilol against Ischemic Hepatitis Associated with Acute Heart Failure via Targeting miRNA-17 and Mitochondrial Dynamics-Related Proteins: An In Vivo and In Silico Study

• Main Authors: Doaa I. Mohamed (Author), Samar F. Ezzat (Author), Wael M. Elayat (Author), Omnyah A. El-Kharashi (Author), Hanaa F. Abd El-Kareem (Author), Hebatallah H. Abo Nahas (Author), Basel A. Abdel-Wahab (Author), Samar Zuhair Alshawwa (Author), Asmaa Saleh (Author), Yosra A. Helmy (Author), Eman Khairy (Author), Essa M. Saied (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute heart failure (AHF) is one of the most common diseases in old age that can lead to mortality. Systemic hypoperfusion is associated with hepatic ischemia-reperfusion injury, which may be irreversible. Ischemic hepatitis due to AHF has been linked to the pathogenesis of liver damage. In the pres...