Metaplastic Regulation of the Median Raphe Nucleus via Serotonin 5-HT1A Receptor on Hippocampal Synaptic Plasticity Is Associated With Gender-Specific Emotional Expression in Rats

• Main Authors: Sumitaka Inoue (Author), Hiroki Shikanai (Author), Machiko Matsumoto (Author), Sachiko Hiraide (Author), Yasuhiro Saito (Author), Yoshiki Yanagawa (Author), Mitsuhiro Yoshioka (Author), Kei-ichi Shimamura (Author), Hiroko Togashi (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gender differences in psychiatric disorders are considered to be associated with the serotonergic (5-HTergic) system; however the underlying mechanisms have not been clearly elucidated. In this study, possible involvement of the median raphe nucleus (MRN)-hippocampus 5-HTergic system in gender-speci...