A distinct profile of tryptophan metabolism along the kynurenine pathway downstream of Toll-like receptor activation in irritable bowel syndrome

• Hlavní autoři: Gerard eClarke (Autor), Declan P McKernan (Autor), Gabor eGaszner (Autor), Eamonn M Quigley (Autor), John F Cryan (Autor), Timothy G Dinan (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2012-05-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Irritable bowel syndrome (IBS), a disorder of the brain-gut axis, is characterised by the absence of reliable biological markers. Tryptophan is an essential amino acid that serves as a precursor to serotonin but which can alternatively be metabolised along the kynurenine pathway leading to the produ...