A distinct profile of tryptophan metabolism along the kynurenine pathway downstream of Toll-like receptor activation in irritable bowel syndrome

• मुख्य लेखकों: Gerard eClarke (लेखक), Declan P McKernan (लेखक), Gabor eGaszner (लेखक), Eamonn M Quigley (लेखक), John F Cryan (लेखक), Timothy G Dinan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2012-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Irritable bowel syndrome (IBS), a disorder of the brain-gut axis, is characterised by the absence of reliable biological markers. Tryptophan is an essential amino acid that serves as a precursor to serotonin but which can alternatively be metabolised along the kynurenine pathway leading to the produ...