Bcl-xL activity influences outcome of the mitotic arrest

• Main Authors: M. Suleimenov (Author), S. Bekbayev (Author), M. Ten (Author), N. Suleimenova (Author), M. Tlegenova (Author), A. Nurmagambetova (Author), S. Kauanova (Author), I. Vorobjev (Author)
• 格式: 圖書
• 出版: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Microtubule-targeting (MT) drugs taxanes and vinca alkaloids are widely used as chemotherapeutic agents against different tumors for more than 30 years because of their ability to block mitotic progression by disrupting the mitotic spindle and activating the spindle assembly checkpoint (SAC) for a p...