Identification of sequence variants associated with severe microtia-astresia by targeted sequencing

• Main Authors: Pu Wang (Author), Yibei Wang (Author), Xinmiao Fan (Author), Yaping Liu (Author), Yue Fan (Author), Tao Liu (Author), Chongjian Chen (Author), Shuyang Zhang (Author), Xiaowei Chen (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Microtia-atresia is characterized by abnormalities of the auricle (microtia) and aplasia or hypoplasia of the external auditory canal, often associated with middle ear abnormalities. To date, no causal genetic mutations or genes have been identified in microtia-atresia patients....