SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation

• मुख्य लेखकों: Yangtian Yan (लेखक), Ningning Yuan (लेखक), Yuchi Chen (लेखक), Yun Ma (लेखक), Ali Chen (लेखक), Fujing Wang (लेखक), Shihua Yan (लेखक), Zhuo'en He (लेखक), Jinyue He (लेखक), Chi Zhang (लेखक), Hao Wang (लेखक), Mingqing Wang (लेखक), Jianxin Diao (लेखक), Wei Xiao (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2024-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Diabetic kidney disease (DKD) represents a microvascular complication of diabetes mellitus. Shenkang Pills (SKP), a traditional Chinese medicine formula, has been widely used in the treatment of DKD and has obvious antioxidant effect. Ferroptosis, a novel mode of cell death due t...