SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation
Abstract Background Diabetic kidney disease (DKD) represents a microvascular complication of diabetes mellitus. Shenkang Pills (SKP), a traditional Chinese medicine formula, has been widely used in the treatment of DKD and has obvious antioxidant effect. Ferroptosis, a novel mode of cell death due t...
Saved in:
Main Authors: | Yangtian Yan (Author), Ningning Yuan (Author), Yuchi Chen (Author), Yun Ma (Author), Ali Chen (Author), Fujing Wang (Author), Shihua Yan (Author), Zhuo'en He (Author), Jinyue He (Author), Chi Zhang (Author), Hao Wang (Author), Mingqing Wang (Author), Jianxin Diao (Author), Wei Xiao (Author) |
---|---|
Format: | Book |
Published: |
BMC,
2024-02-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effects of Shenkang Pills on Early-Stage Diabetic Nephropathy in db/db Mice via Inhibiting AURKB/RacGAP1/RhoA Signaling Pathway
by: Fujing Wang, et al.
Published: (2022) -
LSD1 inhibition by tranylcypromine hydrochloride reduces alkali burn-induced corneal neovascularization and ferroptosis by suppressing HIF-1α pathway
by: Qian Deng, et al.
Published: (2024) -
Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway
by: Zhuanghua Liu, et al.
Published: (2022) -
Interaction between AhR and HIF-1 signaling pathways mediated by ARNT/HIF-1β
by: Mengdi Zhang, et al.
Published: (2022) -
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway
by: Lejing Lou, et al.
Published: (2023)