Enhanced oral bioavailability of an etoposide multiple nanoemulsion incorporating a deoxycholic acid derivative-lipid complex

• Main Authors: Saurav Kumar Jha (Author), Hee-Soo Han (Author), Laxman Subedi (Author), Rudra Pangeni (Author), Jee Young Chung (Author), Seho Kweon (Author), Jeong Uk Choi (Author), Youngro Byun (Author), Yong-Hee Kim (Author), Jin Woo Park (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, a system for oral delivery of etoposide (ETP) was designed to avoid the problems associated with low and variable bioavailability of a commercially available ETP emulsion comprised of polyethylene glycol, glycerol, and citric acid anhydrous. ETP was complexed with low-molecular-weight...