Transcriptomic response of brain tissue to focused ultrasound‐mediated blood-brain barrier disruption depends strongly on anesthesia

• Main Authors: Alexander S. Mathew (Author), Catherine M. Gorick (Author), E. Andrew Thim (Author), William J. Garrison (Author), Alexander L. Klibanov (Author), G. Wilson Miller (Author), Natasha D. Sheybani (Author), Richard J. Price (Author)
• Format: Book
• Published: Wiley, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Focused ultrasound (FUS) mediated blood-brain barrier disruption (BBBD) targets the delivery of systemically‐administered therapeutics to the central nervous system. Preclinical investigations of BBBD have been performed on different anesthetic backgrounds; however, the influence of the cho...