Left Ventricular SGLT1 Protein Expression Correlates with the Extent of Myocardial Nitro-Oxidative Stress in Rats with Pressure and Volume Overload-Induced Heart Failure

• Main Authors: Alex Ali Sayour (Author), Mihály Ruppert (Author), Attila Oláh (Author), Kálmán Benke (Author), Bálint András Barta (Author), Eszter Zsáry (Author), Haoran Ke (Author), Eszter Mária Horváth (Author), Béla Merkely (Author), Tamás Radovits (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myocardial sodium-glucose cotransporter 1 (SGLT1) has been shown to be upregulated in humans with heart failure (HF) with or without diabetes. In vitro studies have linked SGLT1 to increased nitro-oxidative stress in cardiomyocytes. We aimed to assess the relation between left ventricular (LV) SGLT1...