Itaconate Suppresses the Activation of Mitochondrial NLRP3 Inflammasome and Oxidative Stress in Allergic Airway Inflammation

• मुख्य लेखकों: Qiu-Meng Xie (लेखक), Ning Chen (लेखक), Si-Ming Song (लेखक), Cui-Cui Zhao (लेखक), Ya Ruan (लेखक), Jia-Feng Sha (लेखक), Qian Liu (लेखक), Xu-Qin Jiang (लेखक), Guang-He Fei (लेखक), Hui-Mei Wu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Itaconate has emerged as a novel anti-inflammatory and antioxidative endogenous metabolite, yet its role in allergic airway inflammation (AAI) and the underlying mechanism remains elusive. Here, the itaconate level in the lung was assessed by High Performance Liquid Chromatography (HPLC), and the ef...