Yes-associated protein (YAP) and transcriptional coactivator with a PDZ-binding motif (TAZ): a nexus between hypoxia and cancer

• मुख्य लेखकों: Chenxi Zhao (लेखक), Chenming Zeng (लेखक), Song Ye (लेखक), Xiaoyang Dai (लेखक), Qiaojun He (लेखक), Bo Yang (लेखक), Hong Zhu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2020-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Hypoxia is a common feature of solid tumors. As transcription factors, hypoxia-inducible factors (HIFs) are the master regulators of the hypoxic microenvironment; their target genes function in tumorigenesis and tumor development. Intriguingly, both yes-associated protein (YAP) and its paralog trans...