ER stress-induced YAP upregulation leads to chondrocyte phenotype loss in age-related osteoarthritis

• मुख्य लेखकों: Yanchun Gao (लेखक), Haifeng Wei (लेखक), Xiaoyuan Peng (लेखक), Chenchen Wang (लेखक), Hongyi Zhu (लेखक), Junhui Yin (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

BackgroundOsteoarthritis (OA) is a common degenerative joint disease, leading to pain and restricted mobility. Age-related endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of OA, but the underlying mechanisms remain unclear. This study aims to explore the relationship betwee...