ER stress-induced YAP upregulation leads to chondrocyte phenotype loss in age-related osteoarthritis

• Main Authors: Yanchun Gao (Author), Haifeng Wei (Author), Xiaoyuan Peng (Author), Chenchen Wang (Author), Hongyi Zhu (Author), Junhui Yin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundOsteoarthritis (OA) is a common degenerative joint disease, leading to pain and restricted mobility. Age-related endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of OA, but the underlying mechanisms remain unclear. This study aims to explore the relationship betwee...