In Silico Screening Identification of Fatty Acids and Fatty Acid Derivatives with Antiseizure Activity: In Vitro and In Vivo Validation

• Main Authors: Emilia Mercedes Barrionuevo (Author), Estefanía Peralta (Author), Agustín Manzur De Nardi (Author), Juliana Monat (Author), Maximiliano José Fallico (Author), Manuel Augusto Llanos (Author), Luciana Gavernet (Author), Emilio Román Mustafá (Author), Pedro Martin (Author), Alan Talevi (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High fat diets have been used as complementary treatments for seizure disorders for more than a century. Moreover, many fatty acids and derivatives, including the broad-spectrum antiseizure medication valproic acid, have been explored and used as pharmacological agents to treat epilepsy. In this wor...