Aging impairs osteoblast differentiation of mesenchymal stem cells grown on titanium by favoring adipogenesis

• Main Authors: Rodrigo Paolo Flores ABUNA (Author), Camila Tami STRINGHETTA-GARCIA (Author), Leonardo Pimentel FIORI (Author), Rita Cassia Menegati DORNELLES (Author), Adalberto Luiz ROSA (Author), Marcio Mateus BELOTI (Author)
• Format: Book
• Published: University of São Paulo.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Aging negatively affects bone/titanium implant interactions. Our hypothesis is that the unbalance between osteogenesis and adipogenesis induced by aging may be involved in this phenomenon. Objective We investigated the osteoblast and adipocyte differentiation of mesenchymal stem cells (MSCs...