Absence of 4-1BB reduces obesity-induced atrophic response in skeletal muscle

• Main Authors: Ngoc Hoan Le (Author), Chu-Sook Kim (Author), Thai Hien Tu (Author), Byung-Sam Kim (Author), Taesun Park (Author), Jung Han Yoon Park (Author), Tsuyoshi Goto (Author), Teruo Kawada (Author), Tae Youl Ha (Author), Rina Yu (Author)
• Format: Book
• Published: BMC, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Obesity-induced inflammation causes skeletal muscle atrophy accompanied by disruption of oxidative metabolism and is implicated in metabolic complications such as insulin resistance and type 2 diabetes. We previously reported that 4-1BB, a member of the tumor necrosis factor receptor superf...