Ten-year experience with pharmacogenetic testing for DPYD in a national cancer center in Italy: Lessons learned on the path to implementation

• Main Authors: A. Bignucolo (Author), E. De Mattia (Author), R. Roncato (Author), E. Peruzzi (Author), L. Scarabel (Author), M. D'Andrea (Author), F. Sartor (Author), G. Toffoli (Author), E. Cecchin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Awareness about the importance of implementing DPYD pharmacogenetics in clinical practice to prevent severe side effects related to the use of fluoropyrimidines has been raised over the years. Since 2012 at the National Cancer Institute, CRO-Aviano (Italy), a diagnostic DPYD genotyping s...