Paradoxical psoriasis induced by TNF‐α blockade shows immunological features typical of the early phase of psoriasis development

• Main Authors: Luca Fania (Author), Martina Morelli (Author), Claudia Scarponi (Author), Laura Mercurio (Author), Fernanda Scopelliti (Author), Caterina Cattani (Author), Giovanni Luca Scaglione (Author), Tiziano Tonanzi (Author), Maria Antonietta Pilla (Author), Gianluca Pagnanelli (Author), Cinzia Mazzanti (Author), Giampiero Girolomoni (Author), Andrea Cavani (Author), Stefania Madonna (Author), Cristina Albanesi (Author)
• Format: Book
• Published: Wiley, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Immunomodulation with anti‐TNF‐α is highly effective in the treatment of various immune‐mediated inflammatory diseases, including hidradenitis suppurativa (HS). However, this may be responsible for unexpected paradoxical psoriasiform reactions. The pathogenic mechanisms underlying the induc...