Bone marrow mesenchymal stem cells-derived exosomes for penetrating and targeted chemotherapy of pancreatic cancer

• Main Authors: Yu Zhou (Author), Wenxi Zhou (Author), Xinli Chen (Author), Qingbing Wang (Author), Chao Li (Author), Qinjun Chen (Author), Yu Zhang (Author), Yifei Lu (Author), Xiaoyi Ding (Author), Chen Jiang (Author)
• Format: Book
• Published: Elsevier, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic ductal adenocarcinoma (PDAC) is one of the most intractable malignancy, with an only 6% 5-year relative survival rate. The dismal therapeutic effect is attributed to the chemotherapy resistance and unique pathophysiology with abundant inflammatory cytokines and abnormal hyperplasia of ext...