Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy

• Main Authors: Megan E. Rosa‐Caldwell (Author), Seongkyun Lim (Author), Wesley A. Haynie (Author), Jacob L. Brown (Author), John William Deaver (Author), Francielly Morena Da Silva (Author), Lisa T. Jansen (Author), David E. Lee (Author), Michael P. Wiggs (Author), Tyrone A. Washington (Author), Nicholas P. Greene (Author)
• Format: Book
• Published: Wiley, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Muscle atrophy is a common pathology associated with disuse, such as prolonged bed rest or spaceflight, and is associated with detrimental health outcomes. There is emerging evidence that disuse atrophy may differentially affect males and females. Cellular mechanisms contributing...