Polyols Permeability on Caco-2 Cells and Their Effects on Transport of Low-Permeability Drugs

• मुख्य लेखकों: Damien Truffin (लेखक), Olaf Häusler (लेखक), Maryse Martin (लेखक), Sandrine Cotier (लेखक), Jerôme Laparre (लेखक), Manilduth Ramnath (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Some pharmaceutical excipients are able to modify intestinal permeability, thus influencing drug absorption and bioavailability. The effect of four polyols (mannitol, maltitol, sorbitol and xylitol) on the permeability of seven active pharmaceutical ingredients (API), representing different BCS clas...