Bioanalytical method development and validation of milnacipran in rat plasma by LCâMS/MS detection and its application to a pharmacokinetic study

• Egile Nagusiak: Kanchanamala Kanala (Egilea), Nagiat T. Hwisa (Egilea), Babu Rao Chandu (Egilea), Prakash Katakam (Egilea), Mukkanti Khagga (Egilea), B.R. Challa (Egilea), Bhavyasri Khagga (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2013-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

A simple, sensitive and specific liquid chromatographyâtandem mass spectrometry (LCâMS/MS) method was developed for the quantification of milnacipran (MC) in rat plasma by using the liquidâliquid extraction method. Milnacipran-d10 (MCD10) was used as an internal standard (IS). Chromatographic separa...