Detection of cytogenetic changes and chromosomal aneuploidy with fluorescent in situ hybridization in cytological specimens of oral cancers in Fanconi anemia-Proof of concept

• Main Authors: Bruno Eduardo Silva de Araujo (Author), Eunike Velleuer (Author), Ralf Dietrich (Author), Natalia Pomjanski (Author), Isabela Karoline deSantana Almeida Araujo (Author), Martin Schlensog (Author), Susanne Irmtraud Wells (Author), Josephine Christine Dorsman (Author), Martin Schramm (Author)
• Format: Knjiga
• Izdano: Wiley, 2022-02-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract Objectives Fanconi anemia (FA) is a rare inherited DNA instability disorder with a remarkably elevated risk of neoplasia compared with the general population, mainly leukemia and squamous cell carcinoma (SCC). Two thirds of the SCCs arise in the oral cavity and are typically preceded by vis...