Combined <i>In Silico</i> and <i>In Vitro</i> Evidence Supporting an Aurora A Kinase Inhibitory Role of the Anti-Viral Drug Rilpivirine and an Anti-Proliferative Influence on Cancer Cells

• Main Authors: Saiful Islam (Author), Theodosia Teo (Author), Malika Kumarasiri (Author), Martin Slater (Author), Jennifer H. Martin (Author), Shudong Wang (Author), Richard Head (Author)
• 格式: 图书
• 出版: MDPI AG, 2022-09-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

The global burden of cancer necessitates rapid and ongoing development of effective cancer therapies. One promising approach in this context is the repurposing of existing non-cancer drugs for cancer indications. A key to this approach is selecting the cellular targets against which to identify nove...