In Vitro Assessment of ¹⁷⁷Lu-Labeled Trastuzumab-Targeted Mesoporous Carbon@Silica Nanostructure for the Treatment of HER2-Positive Breast Cancer

• Main Authors: Ayça Tunçel (Author), Simone Maschauer (Author), Olaf Prante (Author), Fatma Yurt (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study assessed the effectiveness of a trastuzumab-targeted ¹⁷⁷Lu-labeled mesoporous Carbon@Silica nanostructure (DOTA@TRA/MC@Si) for HER2-positive breast cancer treatment, focusing on its uptake, internalization, and efflux in breast cancer cells. The synthesized PEI-MC@S...