Empagliflozin alleviates atherosclerotic calcification by inhibiting osteogenic differentiation of vascular smooth muscle cells

• Main Authors: Junping Li (Author), Changping Li (Author), Zhaoqi Huang (Author), Chunling Huang (Author), Juanzhang Liu (Author), Tao Wu (Author), Shuwan Xu (Author), Peibiao Mai (Author), Dengfeng Geng (Author), Shuxian Zhou (Author), Kun Zhang (Author), Zhaoyu Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SGLT-2 inhibitors, such as empagliflozin, have been shown to reduce the occurrence of cardiovascular events and delay the progression of atherosclerosis. However, its role in atherosclerotic calcification remains unclear. In this research, ApoE−/− mice were fed with western diet and empagliflozin wa...