Zoledronic Acid Targeting of the Mevalonate Pathway Causes Reduced Cell Recruitment and Attenuates Pulmonary Fibrosis

• Asıl Yazarlar: Lloyd Tanner (Yazar), Jesper Bergwik (Yazar), Andrew B. Single (Yazar), Ravi K. V. Bhongir (Yazar), Jonas S. Erjefält (Yazar), Arne Egesten (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background and aim: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease causing irreparable scarring of lung tissue, with most patients succumbing rapidly after diagnosis. The mevalonate pathway, which is involved in the regulation of cell proliferation, survival, and motility, is targ...