Cytosolic group IVa phospholipase A<sub>2 </sub>mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes <it>in vitro</it>

Cytosolic group IVa phospholipase A<sub>2 </sub>mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes <it>in vitro</it>

<p>Abstract</p> <p>Background</p> <p>Cytosolic gIVaPLA<sub>2 </sub>is a critical enzyme in the generation of arachidonate metabolites and in induction of β<sub>2</sub>-integrin adhesion in granulocytes. We hypothesized that gIVaPLA<sub>2 &l...

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Main Authors: Zhu Xiangdong (Author), Osan Christopher M (Author), Binder David C (Author), Meliton Lucille N (Author), Muñoz Nilda M (Author), Meliton Angelo Y (Author), Dudek Steven M (Author), Leff Alan R (Author)
Format: Book
Published: BMC, 2010-03-01T00:00:00Z.
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