Targeted Delivery of Pennyroyal via Methotrexate Functionalized PEGylated Nanostructured Lipid Carriers into Breast Cancer Cells; A Multiple Pathways Apoptosis Activator

• Main Authors: Amin Mahoutforoush (Author), Leila Asadollahi (Author), Hamed Hamishehkar (Author), Soheil Abbaspour-Ravasjani (Author), Atefeh Solouk (Author), Masoumeh Haghbin Nazarpak (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Pennyroyal is a species of the Lamiaceae family with potent anti-cancer and antioxidant properties. Combining this antioxidant with chemotherapeutic agents enhances the effectiveness of these agents by inducing more apoptosis in cancerous cells. Methods: Here, methotrexate (MTX) combined wi...