Immunohistochemical Study of Laminin-332 γ2 Chain and MMP-9 in High Risk of Malignant Transformation Oral Lesions and OSCC

• Main Authors: Eline Manhães Reid Silva (Author), Vanessa Morais Freitas (Author), Willian Grassi Bautz (Author), Liliana Aparecida Pimenta de Barros (Author), Letícia Nogueira da Gama de Souza (Author)
• Format: Book
• Published: Stilus Optimus, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Oral squamous cell carcinoma is associated with alterations in basement membrane. Laminin-332 is present in basal lamina and performs multiple biologic effects by γ2 chain. Matrix metalloproteinase acts disrupting extracellular components and was related to poor prognosis in cancer. Here...