IGFBP-4 tumor and serum levels are increased across all stages of epithelial ovarian cancer

• Autori principali: Mosig Rebecca A (Autore), Lobl Mollie (Autore), Senturk Emir (Autore), Shah Hardik (Autore), Cohen Samantha (Autore), Chudin Eugene (Autore), Fruscio Robert (Autore), Marchini Sergio (Autore), D'Incalci Maurizio (Autore), Sachidanandam Ravi (Autore), Dottino Peter (Autore), Martignetti John A (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2012-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>We sought to identify candidate serum biomarkers for the detection and surveillance of EOC. Based on RNA-Seq transcriptome analysis of patient-derived tumors, highly expressed secreted proteins were identified using a bioinformatic a...