Population pharmacokinetic analysis of apomorphine sublingual film or subcutaneous apomorphine in healthy subjects and patients with Parkinson's disease

• المؤلفون الرئيسيون: Felix Agbo (مؤلف), Ryan L. Crass (مؤلف), Yu‐Yuan Chiu (مؤلف), Sunny Chapel (مؤلف), Gerald Galluppi (مؤلف), David Blum (مؤلف), Bradford Navia (مؤلف)
• التنسيق: كتاب
• منشور في: Wiley, 2021-07-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Apomorphine is an on‐demand treatment of "OFF" episodes in patients with Parkinson's disease (PD). A joint parent‐metabolite population pharmacokinetic (PK) model characterized apomorphine and apomorphine‐sulfate following administration of apomorphine sublingual film (APL) a...