Endothelium-derived 6-nitrodopamine is the major mechanism by which nitric oxide relaxes the rabbit isolated aorta

• Main Authors: Eric Xavier Dos Santos (Author), José Britto-Júnior (Author), João Victor Ribeiro (Author), Gilberto Quirino Junior (Author), Antonio Tiago Lima (Author), Manoel Odorico Moraes (Author), Maria Elisabete A. Moraes (Author), Edson Antunes (Author), André Schenka (Author), Gilberto De Nucci (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

6-Nitrodopamine (6-ND) is the predominant catecholamine released from isolated vascular tissues in both mammals and reptiles, with its release being significantly reduced by the NO synthesis inhibitor, Nω-nitro-L-arginine methyl ester (L-NAME). The vasorelaxation induced by 6-ND is unaffected by eit...