Bone Marrow-Derived CD44+ Cells Migrate to Tissue-Engineered Constructs via SDF-1/CXCR4-JNK Pathway and Aid Bone Repair

• Những tác giả chính: Yanzhu Lu (Tác giả), Junchao Xing (Tác giả), Xiaolong Yin (Tác giả), Xiaobo Zhu (Tác giả), Aijun Yang (Tác giả), Jiyue Luo (Tác giả), Jing Gou (Tác giả), Shiwu Dong (Tác giả), Jianzhong Xu (Tác giả), Tianyong Hou (Tác giả)
• Định dạng: Sách
• Được phát hành: Hindawi Limited, 2019-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Background and Aims. Host-derived cells play crucial roles in the regeneration process of tissue-engineered constructs (TECs) during the treatment of large segmental bone defects (LSBDs). However, their identity, source, and cell recruitment mechanisms remain elusive. Methods. A complex model was cr...