PDE4 as a target in preterm labour

• Main Authors: Hervé Roxane (Author), Oger Stéphanie (Author), Schmitz Thomas (Author), Méhats Céline (Author), Cabrol Dominique (Author), Leroy Marie-Josèphe (Author)
• Format: Book
• Published: BMC, 2007-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Cyclic nucleotide phosphodiesterases (PDE) are the enzymes catalyzing the hydrolysis and inactivation of the second messengers, cAMP and cGMP. Eleven PDE families are described to date, and selective inhibitors of some PDEs families are currently used in clinic f...